Transcriptomic Plasticity Is a Hallmark of Metastatic Pancreatic Cancer
Published in Cancer Research, 2026
Recommended citation: Jiménez-Sánchez, A., et al. Cancer Research 86(7), 1769–1796 (2026). https://doi.org/10.1158/0008-5472.CAN-25-1117
This study combines single-cell transcriptomics and genomic data to investigate how pancreatic cancer cells adapt across metastatic sites. It examines the relationship between clonal history, transcriptional states, and local tissue environments.